A cartoon shows a head in profile split between a gray region at the front and a green region at the back. In the back is a bell and progressively larger dotted white circles propagate outward from the bell toward the front of the head.
October 7, 2024
The way sensory prediction changes under anesthesia tells us how conscious cognition works
A view of a surgery in progress. Surgeons wearing blue gowns hold a scalpel and scissors just above an opening in the dressing of a patient who is lying on a table. Blurred in the foreground is a tray of other surgical instruments.
September 23, 2024
Research quantifying “nociception” could help improve management of surgical pain
A diagram shows hundreds of dots interconnected by gray lines. Many of the dots show combinations of different colors, denoting which serotonin receptors they express.
September 6, 2024
Better living through brain chemistry
Two panels show the emergence of seizures. Calm, narrow dark blue squiggles representing a tight range of low voltages at various currents explode into vibrant, wide squiggles with warmer colors as current and voltage increases at a broadening range of frequencies.
August 21, 2024
Study assesses seizure risk from stimulating thalamus
Two green-stained cross sections of a mouse brain, one labeled Cuprizone Control and one labeled Cuprizone 40Hz,, are accompanied by insets showing magnifications of parts specific brain regions. The green staining in each inset is greater and brighter in the 40Hz insets vs. the control insets.
August 8, 2024
Study reveals ways in which 40Hz sensory stimulation may preserve brain’s ‘white matter’

Petite & Profound

June 22, 2023
Research Feature
Why studying simple organisms—none larger than the palm of your hand—is so integral to understanding nervous system health, disease and evolution.

Picower postdoc earns Burroughs Wellcome Fund award

June 13, 2023
Picower People
‘Career Award at the Scientific Interface’ recognizes Rebecca Pinals’ research to create a nanosensor-integrated brain-on-a-chip model of Alzheimer’s disease.

Without key extracellular protein, neuronal axons break and synaptic connections fall apart

June 12, 2023
Research Findings
MIT scientists find evidence that a protein common to flies and people is essential for supporting the structure of axons that neurons project to make circuit connections. When those break down, the connections follow suit.

Mind to molecules: Does brain’s electrical encoding of information ‘tune’ sub-cellular structure?

May 22, 2023
Research Findings
Brain waves carry information. A new “Cytoelectric Coupling” hypothesis posits that fluctuating electric fields optimize brain network efficiency and stability by shaping the brain’s molecular infrastructure.

40 Hz vibrations reduce Alzheimer’s pathology, symptoms in mouse models

May 18, 2023
Research Findings
Tactile stimulation improved motor performance, reduced phosphorylated tau, preserved neurons and synapses and reduced DNA damage, a new study shows

From labs to the streets, experts work to defuse childhood threats to mental health

May 18, 2023
Picower Events
Symposium speakers describe numerous ways to promote prevention, resilience, healing and wellness after early life stresses

From molecular to whole-brain scale in a simple animal, study reveals serotonin’s effects

May 15, 2023
Research Findings
With full genetic control and visibility into neural activity and behavior, MIT scientists map out chemical’s role in behavior

Neuroscientists identify cells especially vulnerable to Alzheimer’s

April 19, 2023
Research Findings
Neurons that form part of a memory circuit are among the first brain cells to show signs of neurodegeneration in Alzheimer’s disease.

A new peptide may hold potential as an Alzheimer’s treatment

April 12, 2023
Research Findings
The peptide blocks a hyperactive brain enzyme that contributes to the neurodegeneration seen in Alzheimer’s and other diseases.

Fluid flow in the brain can be manipulated by sensory stimulation

April 10, 2023
Research Findings
Blood flow induced by visual stimulation drives the flow of cerebrospinal fluid

Studying consciousness without affecting it

April 6, 2023
Research Findings
A new study tests an alternative to external stimulation for measuring when subjects lose and regain responsiveness during sedation and anesthesia.

Spring break tours give high schoolers a chance to see science up close

March 31, 2023
Picower Events
Teens from area high schools got the chance to learn about advanced biology and brain research on field trips to MIT