Troy Littleton, the Menicon Professor in Neuroscience in the departments of Biology and Brain and Cognitive Sciences: Littleton works to understand the mechanisms by which neurons form synaptic connections, how synapses transmit information, and how synapses change during learning and memory, as well as how alterations in neuronal signaling underlie several neurological diseases, including epilepsy, autism and Huntington’s disease. Using Drosophilaas a model, Littleton combines molecular biology, protein biochemistry, electrophysiology, and imaging approaches with Drosophila genetics, to investigate the mechanisms underlying synapse formation, function and plasticity.
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